Discovery of Haloperidol
نویسندگان
چکیده
Key words Prins reaction - Friedel–Crafts acylation piperidine schizophrenia
منابع مشابه
Reduced haloperidol/haloperidol ratios after oral haloperidol and decanoate administration in schizophrenics.
1. Haloperidol and reduced haloperidol plasma concentrations were measured in thirteen stable schizophrenic patients that received both oral haloperidol and haloperidol decanoate. 2. Significant correlations between reduced haloperidol/haloperidol ratios from oral haloperidol and haloperidol decanoate occurred at week two and week 16, respectively. 3. The formation of RH was consistent during h...
متن کاملWhich dose of haloperidol?
Although haloperidol (HAL)has been available as an antipsychotic for over 30 years, controversy still surrounds the appropriate dose in the treatment of psychosis and in particular, schizo phrenia. In practice, high dose HAL (greater than 20 mg/day) continues to be prescribed, despite good reason for not doing so: the incidence of extrapyramidal side-effects (EPSE) is known to be dose-related; ...
متن کاملHaloperidol in palliative care.
Haloperidol is one of 20 'essential' medications in palliative care. Its use is widespread in palliative care patients. The pharmacology of haloperidol is complex and the extent and severity of some of its adverse effects, particularly extrapyramidal adverse effects (EPS), may be related to the route of administration. Indications for the use of haloperidol in palliative care are nausea and vom...
متن کاملHaloperidol Decanoate : Route of Administration
Haloperidol decafloate (HPL-D) is a useful depot neuroleptic on several counts : it has a duration of action of 4-6 weeks, there is no dumping effect associated with its administration, and the adverse effects milligram for milligram are fewer and milder than those observed with the oral form of haloperidol (Beresford and Ward, 1987, Glazer and Kane, 1992). HPL-D requires to be administered by ...
متن کاملAngioedema associated with haloperidol.
Haloperidol is one of the antipsychotic medications which are widely used in the emergency department and its association with angioedema which is very rarely reported in scientific literature. One of the serious situations in the emergency department is angioedema and it bends airway obstruction which is need early attention and treatment. A case was reported which was observed at a government...
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ژورنال
عنوان ژورنال: Synfacts
سال: 2023
ISSN: ['1861-194X', '1861-1958']
DOI: https://doi.org/10.1055/s-0042-1751933